|
KMID : 0374920040250010009
|
|
Inje Medical Journal
2004 Volume.25 No. 1 p.9 ~ p.22
|
|
|
Aspirin For Primary Prevention of Coronary Events
|
|
Yi Seong-Yoon
|
|
|
Abstract
|
|
|
|
Aspirin use probably reduces the risk of myocardial infarction in men over the age of 50 years. For individual patients, the decision to initiate aspirin therapy should be based on a careful assessment of absolute risk. The absolute risk of major coronary events should be calculated as the Framingham risk score. This can easily be done in the physician’s office with the use of an on-line or downloaded version of the scoring system (for example, that available at http://www.nhlbi.nih.gov/atpiii/calculator.asp?usertype=prof ). A suggested algorithm for making decisions about the use of aspirin therapy on the basis of predictions of absolute risk is presented in Figure 2. Patients with an estimated risk of coronary events of 1.5 percent per year of higher are, barring contraindications, good candidates for aspirin therapy, whereas those with a risk of 0.6 percent per year or less are probably not. Among patients with an intermediate level of risk -that is, 0.7 to 1.4 percent per year- other factors should be considered, including the preferences of the patient; treatment should be considered more seriously if there is adequately treated hypertension with target-organ damage, diabetes mellitus, or poor physical fitness.
|
|
|
KEYWORD
|
|
|
aspirin, primary prevention
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|